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论文编号: 122214O120120154
第一作者所在部门: 708组
中文论文题目:
英文论文题目: In-vitro cytotoxicity and in-vivo biocompatibility of as-extruded Mg–4.0Zn–0.2Ca alloy
论文题目英文:
作者: 夏永华
论文出处:
刊物名称: Materials Science and Engineering C
: 2012
: 32
: 4
: 665-669
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摘要: In this paper, the in-vitrocytotoxicity?and the in-vivo?compatibility of?Mg–4.0Zn–0.2Caalloy?are studied. The?cytotoxicity?of?Mg–4.0Zn–0.2Caalloy?is examined by MTT method on osteoblast cells. The in-vivobehavior of?Mg–4.0Zn–0.2Caalloy?is investigated on rabbits. It has been found thatMg–4.0Zn–0.2Caalloy?extract has no?cytotoxicity?on osteoblast cells. Three months after in-vivoexperiment, about 35–38% magnesium?alloy?implant has been degraded and a degradation layer which is composed of Ca, P, O and?Mg?has been formed on the magnesium?alloy?implants. Histological analysis showed that new bone is observed around magnesium implant without inflammation reaction. In-vitro?and in-vivo?test indicated that the?Mg–4.0Zn–0.2Caalloy?has good?biocompatibility
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